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Displaying 61 - 70 of 241 in ACP Store

Illinois Northern Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Idaho Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Iowa Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Hawaii Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Georgia Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Florida Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Delaware Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

The District of Columbia Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Connecticut Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

Colorado Chapter Fund

Your chapter donation directly impacts physicians in our area by contributing to chapter programming. When you give, you're investing in: Building Tomorrow's Leaders – Supporting programs and educational initiatives that guide medical students and residents as they develop into skilled Internal Medicine Physicians. Amplifying Our Professional Voice – Enabling our chapter to advocate effectively for policies that advance internal medicine and benefit the patients we serve. Connecting Our Community – Creating opportunities for physicians to collaborate, share knowledge, and support one another throughout their careers. Every contribution, regardless of size, makes a measurable difference in our chapter. Together, we're building a stronger future for internal medicine.

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Displaying 61 - 70 of 500 in Annals of Internal Medicine: Clinical Cases

The Hidden Impact: Insulin Lipohypertrophy | Annals of Internal Medicine: Clinical Cases

Insulin lipohypertrophies (LH) consist of soft-tissue nodules caused by insulin's anabolic properties, potentially leading to erratic insulin absorption, hypoglycemia, and uncontrolled diabetes. A thorough physical examination of insulin injection and pump-insertion sites is crucial for detecting such changes in patients with diabetes. Counseling on rotating injection sites helps prevent LH. Here, we present 2 cases of LH, one in a Hispanic man and one in an African American man, both with long-standing type 1 diabetes mellitus.

Epididymo-Orchitis Leading to Testicular Infarction: Revealing a Potentially Severe Complication of SGLT2 Inhibitors | Annals of Internal Medicine: Clinical Cases

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are not only used for managing type 2 diabetes mellitus (T2DM) but also have been shown to be effective in reducing major cardiovascular events and slowing chronic kidney disease progression. However, they cause glycosuria, which increases the risk for genitourinary (GU) infections. We report a patient with uncontrolled T2DM who developed epididymo-orchitis 6 weeks after starting empagliflozin, which progressed to testicular infarction. Although not well documented, SGLT2 inhibitors may increase the risk for epididymo-orchitis because infections may ascend from the urinary tract. This case highlights the importance of close observation to avoid serious events associated with SGLT2 inhibitors.

Debilitating Periorbital Edema Secondary to Anti-SAE Dermatomyositis | Annals of Internal Medicine: Clinical Cases

Dermatomyositis (DM) is an autoimmune inflammatory myopathy with heterogeneous systemic and cutaneous manifestations. Certain forms of DM have isolated skin findings without overt myositis and are called amyopathic DM. Myositis-specific autoantibodies are associated with distinct phenotypes of DM that can support the diagnosis and better define management and prognostication. We describe a case of amyopathic DM with the presence of the small ubiquitin-like modifier activation enzyme 1 autoantibody presenting with severe, debilitating periorbital edema.

Necrotizing Cavitary Pneumonia by Serratia marcescens in a Patient Treated With Dupilumab: Correlation or Causation? | Annals of Internal Medicine: Clinical Cases

Serratia species are gram-negative bacilli causing opportunistic and nosocomial infections, often in patients who are immunocompromised. A 61-year-old man with severe asthma receiving dupilumab presented with fever and chills. A chest computed tomography scan revealed bilateral cavitary lesions suggestive of necrotizing pneumonia. Bronchoalveolar lavage grew Serratia marcescens, and he was treated with prolonged antibiotics. Serratia marcescens should be considered in necrotizing pneumonia, even in patients who are immunocompetent, with dupilumab potentially as the inciting factor.

Unveiling CYP24A1 Mutation in Unexplained Hypercalcemia in an Adult: A Case Report | Annals of Internal Medicine: Clinical Cases

We present the clinical history of a 60-year-old man with persistent skeletal pain and recurrent renal stones associated to chronic hypercalcemia with fluctuating serum calcium levels. Elevated 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations in the absence of vitamin D supplementation together with a decreased 24,25-dihydroxyvitamin D concentration suggested altered vitamin D metabolism. Genetic testing demonstrated a biallelic loss-of-function mutation in the CYP24A1 gene, responsible for reduced vitamin D inactivation. This rare condition, usually associated with idiopathic infantile hypercalcemia, may manifest later in life. Early recognition and management are critical to prevent complications such as recurrent nephrolithiasis, nephrocalcinosis, and renal failure.

The Mystery of Dropped Gallstones: A Case Series and Review of the Literature | Annals of Internal Medicine: Clinical Cases

Laparoscopic cholecystectomy (LC) is the gold standard general surgical procedure for symptomatic gallbladder (GB) disease. The 2 most common complications of LC are GB perforation and dropped gallstones (DGs). Dropped gallstones mostly stay asymptomatic but can rarely serve as a nidus for infection with delayed formation of abscesses, granulomas, and fistulas after many years. We describe a case series of 2 patients with abdominal abscesses and fistula formation from symptomatic retained DGs presenting many years later as a delayed complication of LC.

From Clonidine Withdrawal to Posterior Reversible Encephalopathy Syndrome: Imaging and Cerebrospinal Fluid Clues in a Case of Hypertensive Emergency | Annals of Internal Medicine: Clinical Cases

We report the case of a 33-year-old man who developed posterior reversible encephalopathy syndrome (PRES) after clonidine withdrawal, which led to a hypertensive crisis. The patient presented with rapid neurologic decline, including vision loss and confusion. Due to the initial unavailability of magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis revealing albuminocytologic dissociation was pivotal in establishing the diagnosis. Subsequent MRI confirmed parieto-occipital hyperintensities, solidifying the PRES diagnosis. This case underscores the diagnostic value of CSF analysis in rapidly evolving neurologic conditions when MRI is delayed or unavailable and highlights the risk for PRES as a complication of clonidine withdrawal.

Evolocumab-Induced Paradoxical Rise of Low-Density Lipoprotein Cholesterol Levels | Annals of Internal Medicine: Clinical Cases

While hyporesponsiveness to proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) has been reported, a rise in low-density lipoprotein cholesterol (LDL-C) is undocumented. This case describes a paradoxical increase in LDL-C following PCSK9i therapy. Possible mechanisms include genetic variability, altered hepatic receptor activity, or compensatory lipid metabolism. A 39-year-old woman with insulin-dependent type II diabetes, hypertension, hypothyroidism, and familial dyslipidemia experienced elevated cholesterol and LDL-C after starting evolocumab, which normalized after discontinuation. Further research is needed to clarify the mechanisms underlying this paradoxical response and assess its clinical relevance.

A Case of Cutaneous and Systemic Plasmacytosis Treated With Tocilizumab | Annals of Internal Medicine: Clinical Cases

Cutaneous and systemic plasmacytosis is a rare lymphoproliferative plasma cell disorder characterized by cutaneous lesions, constitutional symptoms, and polyclonal plasma cell infiltrates. Herein, we describe a middle-aged Vietnamese man diagnosed with cutaneous and systemic plasmacytosis who responded to anti–interleukin-6 receptor antibody tocilizumab and has remained in remission for more than 3 years without tocilizumab-related adverse events.

Rocky Mountain Spotted Fever–Associated Myocarditis | Annals of Internal Medicine: Clinical Cases

A previously healthy 23-year-old enlisted man presented for 2 days of fever, gastrointestinal symptoms, cough, and disseminated rash involving the palms and soles. Initial evaluation revealed leukocytosis, elevated liver enzymes, and hyponatremia. Despite antibiotic therapy for pneumonia, his condition worsened, with development of bilateral pleural effusions and myocarditis. After treatment with doxycycline, methylprednisolone, and furosemide, his symptoms improved. He completed a 7-day antibiotic course. Rocky Mountain spotted fever serology was positive 5 weeks after symptom onset. This case highlights the importance of maintaining a broad differential diagnosis and remaining vigilant for atypical presentations of infections to prevent life-threatening complications.

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