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MKSAP 19 - Errata and Revisions

 

Gastroenterology

 

Disorders of the Liver

Page 59: Drug-Induced Liver Injury. In the first paragraph, the last sentence has been changed to "Use of the Web-based tool LiverTox (www.ncbi.nlm.nih.gov/books/NBK547852/) from the National Institutes of Health can help assess risk for hepatotoxicity." (Added August 2021)

 

Nephrology

 

Clinical Evaluation of Kidney Function

Page 1: Estimation of Glomerular Filtration Rate. In September 2021, the Task Force of the National Kidney Foundation and the American Society of Nephrology recommended the immediate adoption of a new 2021 Chronic Kidney Disease Epidemiology (CKD-EPI) Creatinine Equation, which has been refit to estimate glomerular filtration rate without a race variable. Based on this recommendation, the following revisions have been made:

In the first paragraph, sentence 2, "These formulas take into account" has been replaced with "These formulas may take into account."

In the second paragraph, sentence 2 has been replaced with: "To estimate GFR, the National Kidney Foundation and the American Society of Nephrology recommend using the CKD-EPI Creatinine Equation (2021) (www.kidney.org/professionals/kdoqi/gfr_calculator), which has been refit to estimate kidney function without a race variable (see Table 1). The race-based modifier may lead to inaccurately high GFR estimates in patients who identify as Black. CKD-EPI equations presume standard body surface area and therefore require adjustment for very large or small persons. Combining filtration markers (creatinine and cystatin C) into the CKD-EPI creatinine-cystatin C equation is more accurate and informs clinical decision making better than either marker alone." (Added October 2021)

Page 2: Estimation of Glomerular Filtration Rate, Table 1. Methods for Estimating Kidney Function. To reflect the Task Force of the National Kidney Foundation and the American Society of Nephrology recommendation for the immediate adoption of a new 2021 Chronic Kidney Disease Epidemiology (CKD-EPI) Creatinine Equation, which has been refit to estimate glomerular filtration rate without a race variable, Table 1 was revised as follows:

  • Row 3, column 1. Column heading was revised to "CKD-EPI Creatinine (2021)." In sentence 1, the term "race" was deleted.
  • Row 3, column 3. Sentence 2 was deleted.
  • Row 5, column 3. "The most accurate formula for estimating GFR in most situations" was added.
  • (Added October 2021)

Page 3: Estimation of Glomerular Filtration Rate, Key Points. To reflect the Task Force of the National Kidney Foundation and the American Society of Nephrology recommendation for the immediate adoption of a new 2021 Chronic Kidney Disease Epidemiology (CKD-EPI) Creatinine Equation, which has been refit to estimate glomerular filtration rate without a race variable, the second Key Point was revised to, "To estimate glomerular filtration rate, the National Kidney Foundation and the American Society of Nephrology recommend using Chronic Kidney Disease Epidemiology (CKD-EPI) Creatinine Equation (2021), which has been refit to estimate kidney function without a race variable." (Added October 2021)

 

Chronic Kidney Disease

Page 76: Diagnosis. To reflect the Task Force of the National Kidney Foundation and the American Society of Nephrology recommendation for the immediate adoption of a new 2021 Chronic Kidney Disease Epidemiology (CKD-EPI) Creatinine Equation, which has been refit to estimate glomerular filtration rate without a race variable, the equation in sentence 1 has been revised to "Chronic Kidney Disease Epidemiology (CKD-EPI) Creatinine Equation (2021)." (Added October 2021)

 

Neurology

 

Stroke

Page 36: Primary Prevention. In the first sentence of the first paragraph, the cross-reference should be: MKSAP 19 General Internal Medicine 2. (Added August 2021)

 

Neuromuscular Disorders

Page 83: Paraproteinemic Neuropathy. The cross-reference at the end of the third sentence of this paragraph should be: (See MKSAP 19 Hematology.) (Added August 2021)

Questions

 

Page 111, Question 72: In the question stem, the second sentence of the second paragraph should read: "She has right facial weakness, dysarthria, and right arm and leg weakness with a downward drift, with the leg not touching the examination table." (Added August 2021)