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Displaying 281 - 290 of 7611 in ACP Online

Noteworthy Resources for Well-being

ACP: Design Your Own Well-being ProgramExplore these tools to create a well-being program tailored to any organization's needs and budget.View here!

In the News

September Is Suicide Prevention Awareness MonthThere are many ways to take action, start a conversation, and raise awareness for Suicide Prevention. You can:

From the Trenches

Physician Coaching by Professionally Trained Peers for Burnout and Well-BeingJAMA Network Open: S.B. Kiser, MD, MPH; J.D. Sterns, MD, MPH; P.Y. Lai, MS; Nora K. Horick, MS; K. Palamara, MD

September 19, 2025

ACP Well-being Champions: Promoting Well-being Through Awareness, Advocacy, and Action“Loneliness does not come from having no people about one, but from being unable to communicate t

Patients Before Paperwork

ACP Advocate Newsletter highlights that affect physician well-being and professional fulfillment. ACP Advocacy for Reproductive Health Care Rights to Focus on the States With the U.S. Supreme Court ruling to overturn Roe v. Wade, ACP will work with state chapters to advocate for patient autonomy and access to reproductive health care services.

Noteworthy Resources

Physician Suicide Prevention and the Ethics and Role of a Healing Community: An American College of Physicians Policy Paper Matthew DeCamp, MD, PhD, and Mark Levine, MD, for the ACP Ethics, Professionalism and Human Rights Committee

In the News

Protective Equipment for Physicians' Mental Health By Mollie Frost ACP Internist

From the Trenches

After a Physician Dies by Suicide By Ryan DuBosar ACP Internist This article shares resources and discusses the multiple factors that contribute to physician death by suicide. Highlighted tools include advocating for systems changes, destigmatizing mental health help-seeking in the culture of medicine, and creating supportive communities for those associated with or affected by the tragic event. View here!

ACP Webinars

Know Your Colleagues, Know Yourself: Checking In on Mental HealthLiz Lawrence, MD, FACP

September 16, 2022

Individual and Organizational Resources That Give Agency and Provide Nurturing Safe Spaces and Supportive CommunitiesIf you or someone you know is in crisis, help is available 24/7. Text 741741 or call the National Suicide Prevention Lifeline (988 or 1-800-273-8255) or Disaster Distress Hotline (1-800-985-5990).

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Displaying 281 - 290 of 500 in Annals of Internal Medicine: Clinical Cases

A Couple With False Hellebore Poisoning | Annals of Internal Medicine: Clinical Cases

Veratrum album is a poisonous plant with steroidal alkaloids. It is often confused with Allium tricoccum (ramps), which is used as an alternative to scallion/spring onions. This is a case series of a 43-year-old woman and a 54-year-old man poisoned after consuming raw and cooked false hellebore (Veratrum album), most likely confused with Allium tricoccum, ramps, or wild scallions/onions. They presented with complaints of nausea and vomiting and were noted to be bradycardic and hypotensive on examination. They received intravenous fluids and atropine but one of the patients required admission to the medical intensive care unit after responding poorly to management.

A Case of Emphysematous Cholecystitis | Annals of Internal Medicine: Clinical Cases

An 85-year-old man with no history of biliary intervention or cholecystenteric fistulas presented to the emergency department with right hypochondralgia. Imaging revealed pneumobilia and an emphysematous gallbladder wall, consistent with the presentation of emphysematous cholecystitis. Pneumobilia is a rare finding with emphysematous cholecystitis. Gas production by anaerobic bacteria in the biliary tract could be the cause of pneumobilia.

Drug-Induced Interstitial Lung Disease From PARP Inhibitors (Olaparib and Niraparib) for Ovarian Cancer | Annals of Internal Medicine: Clinical Cases

Poly (ADP-ribose) polymerase (PARP) inhibitors are approved for the treatment of several types of cancers. We report a case of an 80-year-old Japanese woman who developed drug-induced interstitial lung disease (ILD) during treatment with PARP inhibitors (olaparib and niraparib) for ovarian cancer. Bronchoalveolar lavage revealed elevated lymphocytes and eosinophils with no pathogens or malignant cells. After treatment with prednisolone, PARP inhibitor–induced ILD improved. This patient case suggests that PARP inhibitor–induced ILD may be caused by allergic processes with cross-reactivity between PARP inhibitors. Therefore, although further studies are required, switching to another PARP inhibitor in patients with PARP inhibitor–induced ILD should be carefully considered.

Reversible Improvement of Arterial Stenosis and Wall Thickness in Takayasu Arteritis Through Treatment With Tocilizumab | Annals of Internal Medicine: Clinical Cases

Early diagnosis and initiation of treatment in Takayasu arteritis (TA) is important to prevent irreversible arterial changes. A 39-year-old female was diagnosed with active TA. Subcutaneous administration of tocilizumab (162 mg/week) was initiated in combination with prednisolone (30 mg/d). After 21 months, the carotid arterial stenosis and wall thickness had normalized with only slight plaque on echocardiography. After 23 months, computed tomography showed normalization of the overall aortic stenosis and wall thickness. The prednisolone dosage could be reduced to 2 mg/d without relapse for >2 years. Early combination treatment of TA with tocilizumab prevented and normalized vascular stenosis and wall thickness.

Abdominal Pain, Conjunctival Icterus, and Melena in a Man With Recent Endocarditis | Annals of Internal Medicine: Clinical Cases

Gastrointestinal bleeding is a common clinical entity associated with substantial morbidity and mortality. Upper gastrointestinal hemorrhage in particular requires swift recognition and management, and additionally engenders a broad differential diagnosis. Although rare, hemobilia, bleeding from or into the biliary tract, is an important diagnosis to consider at the bedside because of its unique risk factors, as well as diagnostic and therapeutic considerations. Here, we describe the clinical presentation of a man with hemobilia, highlighting key contemporary risk factors, diagnostic modalities, and therapeutic interventions.

Brownish-Yellow Layering on Skin—an Unusual Manifestation of Cutaneous Aspergillosis in a Heart Transplant Recipient | Annals of Internal Medicine: Clinical Cases

An unusual cutaneous manifestation of aspergillosis in an immunocompromised patient in which Aspergillus terreus grew on the necrotic skin, creating a brownish-yellow layer of fungal growth, is reported.

A Rare Case of Kleine–Levin Syndrome Following COVID-19 | Annals of Internal Medicine: Clinical Cases

A wide variety of neuropsychiatric manifestations have been reported with COVID-19. We present a case of a 45-year-old man who developed significant hypersomnia and hypersexual thoughts following COVID-19 illness. Further evaluation did not reveal any other infection, structural brain disease, or stroke, leading us to consider Kleine–Levin syndrome as a diagnosis of exclusion. However, a confirmed diagnosis of this syndrome cannot be made on initial presentation, and its formal diagnosis requires recurrence of symptoms. Although relapses of this syndrome are known to be triggered by viral illnesses, no primary occurrences have been reported with COVID-19 to date.

Opsoclonus-Myoclonus Syndrome Possibly Associated With Mumps Infection | Annals of Internal Medicine: Clinical Cases

Opsoclonus-myoclonus syndrome (OMS) is an infrequent yet serious neurologic entity related to neoplastic, infectious, toxic, and metabolic diseases. In recent years, OMS associated with multiple infections have been reported. In contrast to neoplastic and autoimmune etiologies, OMS from infectious diseases occurs in younger patients and has a favorable outcome. Though the data are limited, the use of corticosteroids and immunotherapy remain the treatments of choice for the management of OMS symptoms. We present a patient case of OMS possibility associated with mumps virus in an immunocompetent young adult who was successfully treated with steroids.

Plasma Cell Myeloma With Lymphoplasmacytic Morphology and Negative CD138 Expression: Case Report and Differential Diagnosis | Annals of Internal Medicine: Clinical Cases

Plasma cell neoplasms may have variable morphologic and immunophenotypic features. This patient case demonstrates a rare presentation of plasma cell myeloma with negative CD138 expression and lymphoplasmacytic morphology. In this report, we discuss the possible differential diagnosis and highlight the importance of a comprehensive diagnostic approach including flow cytometry, immunohistochemistry, and molecular studies to arrive at the correct diagnosis.

Recurrent Cryptogenic Stroke in a Young Woman: Congenital Thrombotic Thrombocytopenic Purpura Unmasked | Annals of Internal Medicine: Clinical Cases

Cryptogenic stroke of undetermined cause should warrant an exhaustive neurologic and cardiovascular workup. If no cause is identified, additional investigations should be individualized on the basis of clinical history and objective findings. Herein, we present the case of a young patient with a personal and family history of cryptogenic stroke who was investigated for thrombophilia. Transient thrombocytopenia and peripheral blood schistocytes led to an eventual diagnosis of congenital thrombotic thrombocytopenic purpura, which is characterized by vaso-occlusive end-organ complications. The diagnosis is confirmed by undetectable ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motifs, member 13) activity.

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