MKSAP 19 "Quiz Me!" Question

Test your medical knowledge each month with questions from The Medical Knowledge Self-Assessment Program® (MKSAP).


For over 50 years, the Medical Knowledge Self-Assessment Program (MKSAP) has been the most trusted resource in continuous learning for internal medicine physicians and residents. The tradition continues with MKSAP 19.

MKSAP 19, to be released in early 2022, is available in several flexible formats, allowing you to choose the format that best fits your lifestyle. Each format includes 12 syllabus sections and 1,200 associated deep-learning self-assessment questions.

Learn about the new features in MKSAP 19, as well as pricing and release dates.


A 66-year-old woman is evaluated for a 10-year history of pain in the hands and knees. She has tried occupational therapy, with minimal benefit; she is enrolled in a weight loss program. She has hypertension and chronic kidney disease. Current medications are lisinopril and amlodipine.

On physical examination, Heberden and Bouchard nodes are present and there is carpometacarpal joint tenderness. The medial joint line of each knee is tender to palpation. There is bony enlargement of the medial knees, with crepitus on range of motion.

Laboratory evaluation shows a serum creatinine level of 2.2 mg/dL (194.5 μmol/L) and an estimated glomerular filtration rate of 45 mL/min/1.73 m2.

Which of the following is the most appropriate treatment?

A: Hydrocodone
B: Meloxicam
C: Topical capsaicin
D: Topical diclofenac
E: Topical lidocaine

Answer and Critique

Back to the August 2022 issue of ACP IMpact