ACP Paper Details Transparent and Trustworthy Methods for Developing Evidence-Based Living, Rapid Practice Points

PHILADELPHIA, May 25, 2021 – The American College of Physicians (ACP) today released a paper that details the methods that its Scientific Medical Policy Committee (SMPC) uses to develop ACP living, rapid practice points. The Development of Living, Rapid Practice Points: Summary of Methods From the Scientific Medical Policy Committee of the American College of Physicians, was published in Annals of Internal Medicine.

ACP began developing living, rapid practice points in response to the urgent need to provide evidence-based answers to clinicians managing patients with COVID-19. This process involves evidence gathered through an independent living, rapid systematic review from which practice points are developed. In developing the practice points, ACP takes into account the balance of benefits and harms and also considers public and patient values and preferences, and other considerations including, but not limited to, cost, acceptability, and feasibility.

The paper explains in detail ACP’s methods for developing trustworthy rapid clinical advice, which includes a rapid systematic review, use of the GRADE (Grading of Recommendations Assessment, Development and Evaluation) method to rate the certainty of evidence for outcomes of interest, use of stringent policies on the disclosure of interests and management of conflicts, and incorporating a public (non-clinician) perspective.

“It’s important to transparently detail our methodology and process for developing the living, rapid practice points,” said George Abraham, MD, MPH, FACP, President, ACP. “We want to ensure that clinicians, their patients and others understand the rigorous standards that ACP is known for and were used to develop these timely and topical papers.”

When the ACP rapid practice points are based on evidence that is limited or evolving quickly, such as with the COVID-19 pandemic, the systematic review and practice points are maintained as “living” documents through ongoing surveillance and synthesis of new evidence as it emerges.


About the American College of Physicians
The American College of Physicians is the largest medical specialty organization in the United States with members in more than 145 countries worldwide. ACP membership includes 163,000 internal medicine physicians (internists), related subspecialists, and medical students. Internal medicine physicians are specialists who apply scientific knowledge and clinical expertise to the diagnosis, treatment, and compassionate care of adults across the spectrum from health to complex illness. Follow ACP on TwitterFacebook and Instagram.

ACP Media Contact: Andrew Hachadorian, (215) 351-2514,