Presented at the Internal Medicine Meeting 2021 as a joint session of the American College of Physicians and the European Federation of Internal Medicine (EFIM), this video addresses challenges and opportunities regarding equity in preventive medicine, addressing risk factors, aspirational goals, and practical tips to advance health equity and social determinants of health. Eileen Barrett, MD, MPH, SFHM, MACP, Associate Professor of Medicine, Director of CME, University of New Mexico - serves as the moderator. Sue S. Bornstein, MD, FACP, Chair, ACP Board of Regents and Executive Director, Texas Medical Home Initiative and Nicola Montano, MD, PhD, Immediate Past President, EFIM and Professor of Medicine, University of Milan - serve as panelists in this lively discussion.