MKSAP 19 "Quiz Me!" Question

Test your medical knowledge each month with questions from the Medical Knowledge Self-Assessment Program® (MKSAP).

MKSAP 19MKSAP has been trusted by internal medicine physicians since 1967 as the best resource for updating knowledge. MKSAP 19, available in Complete, Digital, and Print packages, consists of 11 comprehensive text chapters with related multiple-choice questions. You'll find 1,200 completely new questions to help you identify learning gaps, stay current, and gain the knowledge you need to provide the best possible patient care. MKSAP 19's original and high-quality questions evolve out of case studies and patient scenarios based on the latest evidence.

For more information on MKSAP 19, or to order your copy, visit

MKSAP 19 Q & A

A 44-year-old woman is evaluated for hemochromatosis. Her father was recently diagnosed with hemochromatosis following evaluation of cryptogenic cirrhosis. She takes no medications.

On physical examination, vital signs and examination findings are normal.

Iron studies show a ferritin level of 100 ng/mL (100 μg/L), an iron level of 98 μg/dL (18 μmol/L), and transferrin saturation of 35%.

Heterozygous C282Y mutation of the HFE gene is discovered on genetic testing, without H63D or S65C mutation.

Which of the following is the most appropriate management?

A: Iron chelation therapy
B: Phlebotomy
C: Serial iron studies
D: No intervention

Answer and Critique

Back to the September 2023 issue of ACP IMpact