Search Results for "depression"

These Annals of Internal Medicine results only contain recent articles.

Gabapentin reduced drinking in patients with alcohol use disorder and alcohol withdrawal symptoms

Source Citation Anton RF, Latham P, Voronin K, et al. Efficacy of gabapentin for the treatment of alcohol use disorder in patients with alcohol withdrawal symptoms: a randomized clinical trial. JAMA Intern Med. 2020;180:1-9. 32150232

Insufficient evidence for benefits/harms of cognitive impairment screening in asymptomatic older adults

Source Citation US Preventive Services Task Force, Owens DK, Davidson KW, et al. Screening for cognitive impairment in older adults: US Preventive Services Task Force recommendation statement. JAMA. 2020;323:757-63. 32096858

Review: In multiepisode schizophrenia, most antipsychotic drugs improve symptoms; adverse effects vary by drug

Source Citation Huhn M, Nikolakopoulou A, Schneider-Thoma J, et al. Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis. Lancet. 2019;394:939-51. 31303314

Review: In nonsurgical settings, tranexamic acid reduces mortality and does not increase thrombotic events

Source Citation Chornenki NLJ, Um KJ, Mendoza PA, et al. Risk of venous and arterial thrombosis in non-surgical patients receiving systemic tranexamic acid: a systematic review and meta-analysis. Thromb Res. 2019;179:81-6. 31100632

Guideline: USPSTF recommends preexposure prophylaxis with antiretroviral therapy for persons at high risk for HIV

Source Citation US Preventive Services Task Force, Owens DK, Davidson KW, et al. Preexposure prophylaxis for the prevention of HIV infection: US Preventive Services Task Force recommendation statement. JAMA. 2019;321:2203-13. 31184747

The T2Bacteria Panel had 90% sensitivity for detecting targeted organisms, 43% for any bloodstream infection organism

Source Citation Nguyen MH, Clancy CJ, Pasculle AW, et al. Performance of the T2Bacteria Panel for diagnosing bloodstream infections: a diagnostic accuracy study. Ann Intern Med. 2019;170:845-52. 31083728

After stroke due to ICH while on antithrombotics, starting vs avoiding antiplatelets did not differ for symptomatic ICH

Source Citation RESTART Collaboration. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet. 2019;393:2613-23. 31128924

Midazolam or haloperidol premedication reduced ketamine-induced recovery agitation and increased ED recovery time

Source Citation Akhlaghi N, Payandemehr P, Yaseri M, Akhlaghi AA, Abdolrazaghnejad A. Premedication with midazolam or haloperidol to prevent recovery agitation in adults undergoing procedural sedation with ketamine: a randomized double-blind clinical trial. Ann Emerg Med. 2019. [Epub ahead of print]. 30611640

Review: In generalized anxiety disorder, network meta-analysis shows efficacy and tolerability of various drugs

Source Citation Slee A, Nazareth I, Bondaronek P, et al. Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis. Lancet. 2019;393:768-77. 30712879

Review: In adults with chest pain, a HEART score ≥ 4 has 96% sensitivity and 45% specificity for predicting MACE

Source Citation Fernando SM, Tran A, Cheng W, et al. Prognostic accuracy of the HEART score for prediction of major adverse cardiac events in patients presenting with chest pain: a systematic review and meta-analysis. Acad Emerg Med. 2019;26:140-51. 30375097