Search Results for "depression"

Displaying 31 - 30 of 10 in Online Learning Center
Previous
Displaying 31 - 30 of 13 in Performance Measures
Previous
Displaying 31 - 40 of 1481 in Annals of Internal Medicine

These Annals of Internal Medicine results only contain recent articles.

Annals Graphic Medicine - Is This What Depression Looks Like?

Moderate- to Long-Term Effect of Dietary Interventions for Depression and Anxiety

Moderate- to Long-Term Effect of Dietary Interventions for Depression and Anxiety

Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 4)

Update Alert 4: Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians

Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 3)

Update Alert 3: Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis for a Clinical Guideline by the American College of Physicians

Annals Video Summary - Moderate- to Long-Term Effect of Dietary Interventions for Depression and Anxiety: A Systematic Review and Meta-analysis

In nonseasonal depressive disorders, bright light therapy improves response and remission rates

Clinical Impact Ratings Mental Health: 5 out of 7 GIM/FP/GP: 6 out of 7

Surveillance Note 1: Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians

Previous See more results in Annals of Internal Medicine
Displaying 31 - 40 of 75 in Annals of Internal Medicine: Clinical Cases

Clopidogrel Nonresponsiveness Mimicking Endocarditis After PFO-Occlusion: Combining Aspiration, Retrieval, and Laboratory Assessment for Diagnostic-Therapeutic Work-Up | Annals of Internal Medicine: Clinical Cases

Percutaneous patent foramen ovale (PFO) closure lowers recurrent stroke risk but can rarely cause device thrombosis or infection. A 57-year-old woman had elective PFO closure with a GORE CARDIOFORM Septal Occluder device after cerebellar infarction. Despite aspirin and clopidogrel, she developed fever. Transesophageal echocardiography revealed large thrombi on the device. Multidisciplinary management achieved percutaneous retrieval 1-week postimplantation. Cultures were negative. Platelet testing confirmed aspirin effect but showed clopidogrel nonresponsiveness, leading to anticoagulation. Follow-up imaging demonstrated thrombus regression. This case highlights early device thrombosis mimicking infection, successful percutaneous retrieval, and the value of platelet function testing in guiding therapy.

Thymic Hyperplasia in Graves’ Disease: A Case Report | Annals of Internal Medicine: Clinical Cases

Thymic hyperplasia can occur secondary to Graves’ disease, although the exact mechanism is not yet entirely understood. Thymic hyperplasia in this setting is typically benign and improves with treatment of Graves’ disease. Invasive procedures are generally not required but should be considered if suspicion for other underlying disease processes (including malignancy) is suspected and/or imaging does not show thymus regression after antithyroid therapy.

Correction: Retatrutide-Induced Intractable Diarrhea | Annals of Internal Medicine: Clinical Cases

When Cancer Pulls the Bowel In: Intussusception in a Young Adult Man | Annals of Internal Medicine: Clinical Cases

Adult intussusception is a rare cause of bowel obstruction. Unlike pediatric cases, which are common and usually idiopathic, adult intussusception accounts for approximately 5% of all cases and causes about 1% of bowel obstructions. It is almost always associated with a structural lead point, with malignancy accounting for up to 50% of cases. Clinical presentation is often nonspecific, leading to delayed diagnosis and increased morbidity. We present the case of a 28-year-old man with colocolonic intussusception caused by poorly differentiated invasive mucinous adenocarcinoma of the colon in the absence of family history or constitutional symptoms.

Nutcracker Syndrome in an Adult With Recurrent Gross Hematuria Successfully Managed With Conservative Therapy | Annals of Internal Medicine: Clinical Cases

A 27-year-old man with no medical history began passing blood clots in his urine after significant weight loss. Imaging revealed nutcracker syndrome, with compression of his left renal vein by his superior mesenteric artery and aorta. His symptoms resolved after an intensive weight gain regimen. Despite maintaining his weight, his hematuria recurred 2 years later after worsening lumbar lordosis. After a period of strength and flexibility training, his symptoms never returned. This case highlights the clinically diagnostic features of nutcracker syndrome and the elements of successful conservative management in an adult.

Terminal Kidney Failure in a Patient With Renal Involvement of Chronic Lymphocytic Leukemia | Annals of Internal Medicine: Clinical Cases

Chronic lymphocytic leukemia (CLL) rarely causes clinically significant renal involvement, particularly in early-stage disease. We report a patient with Binet stage A CLL who developed progressive renal dysfunction due to probable diffuse leukemic infiltration of the kidneys. Diagnostic evaluation included blood studies, urinalysis, and ultimately kidney biopsy confirming dense interstitial accumulation of CD20−/CD23+ B cells. Ibrutinib therapy was well tolerated but kidney function did not recover. This case highlights that even low-stage CLL may present with organ infiltration and that unexplained renal impairment warrants early consideration of leukemic involvement.

Decoding a Case of Mpox Mimicry in a Patient With Fever and Bloody Diarrhea | Annals of Internal Medicine: Clinical Cases

Mpox, a zoonotic infection increasingly reported outside endemic regions, can mimic other sexually transmitted and enteric infections. We describe a 21-year-old HIV-negative man who presented with fever, bloody diarrhea, and a pustular rash. Work-up revealed co-infection with herpes simplex virus type 1 proctitis, Campylobacter jejuni colitis, and group A Streptococcus bacteremia. Despite antiviral therapy, persistent rash led to biopsy-confirmed Mpox. The patient recovered with supportive care alone. This case underscores the diagnostic challenges posed by overlapping infections and highlights the need to consider Mpox in atypical proctitis and rash presentations among at-risk populations.

An Unrecognized Case of Glanzmann Thrombasthenia Associated With Gastrointestinal Bleeding | Annals of Internal Medicine: Clinical Cases

Glanzmann thrombasthenia (GT) is a rare autosomal-recessive platelet disorder caused by deficiency or dysfunction of glycoprotein IIb/IIIa, resulting in defective aggregation and mucocutaneous bleeding. We report a 22-year-old Egyptian man presenting with gastrointestinal bleeding, severe anemia, and lifelong unexplained bleeding. Endoscopy revealed edematous gastropathy with postbiopsy bleeding exacerbation. Common coagulopathies were excluded and platelet aggregation tests showed absent responses to adenosine diphosphate, collagen, and arachidonic acid, confirming GT by flow cytometry. He was successfully treated with recombinant activated factor VII and tranexamic acid. This case underscores the importance of considering GT in patients with unexplained mucocutaneous bleeding and normal coagulation.

Retatrutide-Induced Intractable Diarrhea | Annals of Internal Medicine: Clinical Cases

Gastrointestinal symptoms accompanying the use of glucagon-like peptide-1 (GLP-1) receptor agonists and glucose-dependent insulinotropic polypeptide receptor-GLP-1 receptor co-agonists have been extensively catalogued. This case report contains a dramatic presentation of unintended consequences from the use of a novel triple-hormone receptor agonist and points toward the need for increased regulatory measures regarding the marketing of these treatments.

Attenuated Cardiac–Ocular Phenotype of Sanfilippo Syndrome (MPS IIIA) Presenting With Hypertrophic Cardiomyopathy and Cone-Rod Dystrophy | Annals of Internal Medicine: Clinical Cases

We describe a 39-year-old woman with cone-rod dystrophy and hypertrophic obstructive cardiomyopathy complicated by an apical aneurysm, ventricular tachycardia, and ischemic stroke, ultimately requiring heart transplantation. Histopathology revealed myocardial storage vacuoles, and biochemical and genetic testing confirmed Sanfilippo syndrome type IIIA (MPS IIIA) with 1 known pathogenic and 1 novel likely pathogenic SGSH mutation. This case illustrates an attenuated cardiac–ocular phenotype of MPS IIIA and emphasizes the need to consider late-onset lysosomal storage disorders in adults with unexplained hypertrophic cardiomyopathy.

Previous See more results in Annals of Internal Medicine: Clinical Cases