ACP Comments on CMS Certification Frequency and Requirements for the Reporting of Quality Measures RFI

Written Testimony to the House Small Business Committee on Medical Student Loan Debt

A Prescription for a Forward-Looking Agenda to Improve American Health Care

Documentation Guidelines for Evaluation and Management Services and Resource-Based Practice Expenses, Private Contracting, Physician Self-Referral Rules, Privacy and Confidentiality, and Regional Laboratory Carriers. Statement for the Practicing Physician Advisory Council.

Rural Primary Care

Occupational and Environmental Medicine: The Internist's Role

Nurse Practitioners in Primary Care

Medical Liability Reform: Innovative Solutions for a New Health Care System

Inner-City Health Care

Home Health Care

Mental Health Treatment for Front-Line Clinicians During and After the Coronavirus Disease 2019 (COVID-19) Pandemic: A Plea to the Medical Community

This Time Must Be Different: Disparities During the COVID-19 Pandemic

Sexual Health in the SARS-CoV-2 Era

Sex and Gender Differences in Health: What the COVID-19 Pandemic Can Teach Us

Annals for Hospitalists Inpatient Notes - Preparing for Battle: How Hospitalists Can Manage the Stress of COVID-19

Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes: Results From a Randomized Trial: Annals of Internal Medicine: Vol 173, No 6

Background: The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or those with a low body weight presenting with an acute coronary syndrome (ACS) are unknown. Objective: To investigate the effect of an age- and weight-adapted dose of prasugrel versus a standard dose of ticagrelor in patients with ACS. (ClinicalTrials.gov: NCT01944800) Design: Prespecified analysis of the multicenter, randomized ISAR-REACT 5 trial. Setting: 23 centers in Germany and Italy. Patients: 3997 patients with ACS planned for invasive management. Intervention: Participants were randomly assigned to receive a standard dose of ticagrelor or prasugrel (reduced dose in the elderly or low-weight group and standard dose in the neither elderly nor low-weight group). Measurements: The efficacy end point was a composite of death, myocardial infarction, or stroke, and the safety end point was bleeding, both at 12 months. Results: In the elderly or low-weight group, the efficacy end point occurred in 12.7% of patients assigned to receive prasugrel and 14.6% of those assigned to receive ticagrelor (hazard ratio [HR], 0.82 [95% CI, 0.60 to 1.14]); in the neither elderly nor low-weight group, the efficacy end point occurred in 4.8% of patients assigned to receive prasugrel and 7.3% of those assigned to receive ticagrelor (HR, 0.65 [CI, 0.48 to 0.88]; P for interaction > 0.2). In the elderly or low-weight group, Bleeding Academic Research Consortium type 3 to 5 bleeding occurred in 8.1% of patients assigned to receive prasugrel and 10.6% of those assigned to receive ticagrelor (HR, 0.72 [0.46 to 1.12]), and in 3.7% and 3.8%, respectively, of patients in the neither elderly nor low-weight group (HR, 0.98 [CI, 0.65 to 1.47]; P for interaction > 0.2). Limitation: The study is a subgroup analysis. Conclusion: In elderly or low-weight patients with ACS, a reduced dose of prasugrel compared with the standard dose of ticagrelor is associated with maintained anti-ischemic efficacy while protecting these patients against the excess risk for bleeding. Primary Funding Source: German Center for Cardiovascular Research and Deutsches Herzzentrum München.

Coronavirus Disease 2019 (COVID-19) and Firearms in the United States: Will an Epidemic of Suicide Follow?

Caution Warranted: Using the Institute for Health Metrics and Evaluation Model for Predicting the Course of the COVID-19 Pandemic

Intersecting U.S. Epidemics: COVID-19 and Lack of Health Insurance

The Role of Medical Students During the COVID-19 Pandemic

Anthrax checklist, email security | ACP Hospitalist

Parkinson's disease | ACP Hospitalist

Online ratings, sleep, and more | ACP Hospitalist

The ABCs of DRGs | ACP Hospitalist

Treatment of trainees, admission patterns, and more | ACP Hospitalist

Stroke transfers, order volume | ACP Hospitalist

Working up inpatient psychosis | ACP Hospitalist

Care management, attending supervision, and more | ACP Hospitalist

Cases from the University of Wisconsin | ACP Hospitalist

Linking severe sepsis and hyperlactatemia | ACP Hospitalist