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In insulin-treated type 1 diabetes, canagliflozin increased diabetic ketoacidosis

Source Citation Peters AL, Henry RR, Thakkar P, Tong C, Alba M. Diabetic ketoacidosis with canagliflozin, a sodium-glucose cotransporter 2 inhibitor, in patients with type 1 diabetes. Diabetes Care. 2016;39:532-8. 26989182

In type 1 diabetes, adding liraglutide to insulin increased hypoglycemia and hyperglycemia with ketosis

Source Citation Mathieu C, Zinman B, Hemmingsson JU, et al. Efficacy and safety of liraglutide added to insulin treatment in type 1 diabetes: The ADJUNCT ONE treat-to-target randomized trial. Diabetes Care. 2016;39:1702-10. 27506222

Review: In adults with diabetes, aspirin does not prevent CV events compared with placebo

Source Citation Kunutsor SK, Seidu S, Khunti K. Aspirin for primary prevention of cardiovascular and all-cause mortality events in diabetes: updated meta-analysis of randomized controlled trials. Diabet Med. 2016. [Epub ahead of print]. 27086572

In abstinent adults with type 2 diabetes, a daily glass of wine (vs mineral water) improved cardiometabolic factors

Source Citation Gepner Y, Golan R, Harman-Boehm I, et al. Effects of initiating moderate alcohol intake on cardiometabolic risk in adults with type 2 diabetes: a 2-year randomized, controlled trial. Ann Intern Med. 2015;163:569-79. 26458258

In patients with type 2 diabetes and CV disease, empagliflozin reduced a composite of CV events at 3.1 years

Source Citation Zinman B, Wanner C, Lachin JM, et al; EMPA-REG OUTCOME Investigators. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;Sep 17. [Epub ahead of print.] 26378978

Review: In diabetes, benefits of lowering BP depend on baseline BP being 140 mm Hg or more

Source Citation Brunström M, Carlberg B. Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses. BMJ. 2016;352:i717. 26920333

Diabetes and other comorbid conditions were associated with a poor outcome in SARS | ACP Journal Club

Source Citation Booth CM, Matukas LM, Tomlinson GA, et al. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA. 2003;289:2801-9. 12734147

Simvastatin reduced mortality and vascular events in diabetes mellitus | ACP Journal Club

Source Citation Collins R, Armitage J, Parish S, et al. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361:2005-16. 12814710

In type 2 diabetes, tirzepatide reduced HbA1c vs. semaglutide

Source Citation Frias JP, Davies MJ, Rosenstock J, et al. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med. 2021;385:503-15. 34170647

In type 1 diabetes, real-time vs. intermittently scanned continuous glucose monitoring improved glycemic control

Source Citation Visser MM, Charleer S, Fieuws S, et al. Comparing real-time and intermittently scanned continuous glucose monitoring in adults with type 1 diabetes (ALERTT1): a 6-month, prospective, multicentre, randomised controlled trial. Lancet. 2021;397:2275-83. 34089660