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Displaying 91 - 100 of 1988 in Annals of Internal Medicine
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Displaying 91 - 100 of 138 in Annals of Internal Medicine: Clinical Cases
Blastomycosis Pneumonia as an Unusual Cause of Horner Syndrome: Case Report and Review | Annals of Internal Medicine: Clinical Cases
We describe an immunocompetent patient with Horner syndrome secondary to invasive Blastomyces pneumonia and provide a review of the rare infectious etiologies of this syndrome. To our knowledge, this is the first published human case report of Horner syndrome secondary to Blastomyces pneumonia.
Colon Perforation in the Setting of Sevelamer Crystals | Annals of Internal Medicine: Clinical Cases
Sevelamer is frequently used as a phosphate binder in patients with end-stage renal disease. It can also cause gastrointestinal side effects including colitis, obstruction, and, rarely, perforation.
Human Disease Caused by Kalamiella piersonii | Annals of Internal Medicine: Clinical Cases
Rare or unusual bacteria in blood cultures can be a diagnostic challenge. Here, we report a case of Kalamiella piersonii, a novel gram-negative Enterobacterales belonging to the proposed genus Kalamiella gen nov in the Erwiniaceae family. A 56-year-old woman with a medical history of end-stage nonischemic cardiomyopathy, receiving milrinone through a tunneled catheter, presented to our emergency department with chills and was found to be bacteremic with gram-negative bacilli identified as K piersonii. She was treated with 14 days of intravenous piperacillin-tazobactam without complications.
Severe Rhabdomyolysis After COVID-19 Vaccine | Annals of Internal Medicine: Clinical Cases
A 65-year-old man presented with muscle pain and muscle weakness lasting 1 week that started after his second BNT162b2 COVID-19 vaccine. He had been taking rosuvastatin and gemfibrozil for several years. He was diagnosed with acute kidney failure caused by rhabdomyolysis resulting from a statin-fibrate interaction from a COVID-19 vaccination and was admitted for continuous venovenous hemodiafiltration. Rhabdomyolysis following messenger RNA COVID-19 vaccination is a rare but important adverse event in patients using high-dose statins combined with fibrates. Such patients should be warned to seek medical attention in case of ongoing muscle symptoms after vaccination.
Immune Checkpoint Inhibitor Use in Microscopic Colitis | Annals of Internal Medicine: Clinical Cases
Immune checkpoint inhibitors (ICIs) are a novel class of anticancer therapies that can result in autoimmune pathology known as immune-related adverse events (irAEs). Because of the risk for irAEs, patients with preexisting autoimmune diseases have been excluded from safety trials for ICIs. Although the pathophysiology of microscopic colitis is not fully understood, it is considered part of the spectrum of immune-mediated gastrointestinal diseases. Little is known about the effects of ICIs on patients with microscopic colitis. This case series describes 4 patients with microscopic colitis requiring ICIs for cancer therapy and gastrointestinal-related outcomes after ICI therapy.
An Uncommon Cause of Cardiac Arrest: Tamponade Secondary to Malignant Pericardial Effusion From Myxoid Sarcoma | Annals of Internal Medicine: Clinical Cases
Primary tumors involving the pericardium are rare and often are incidentally discovered with transthoracic echocardiography. These tumors cause complications from obstruction of cardiac function with hemodynamic instability. We present a case of a 30-year-old man with primary myxoid sarcoma that resulted in cardiac arrest from malignant pericardial effusion. Despite partial resection and chemotherapy, the patient died. Despite being rare, with a 2-year survival of 60%, it is important for clinicians to be able to recognize complications from this tumor. Although no formal guidelines exist, performing surveillance echocardiography in this patient population could prevent some complications.
Hospital Stay Considerations in Hypermobile Ehlers-Danlos Syndrome: An Exemplary Case With Insights for Coexisting Symptoms | Annals of Internal Medicine: Clinical Cases
Ehlers-Danlos syndrome, hypermobility type, is a complex medical condition understood to be a genetic disorder resulting in abnormal collagen synthesis. It is characterized by joint hypermobility as well as skin laxity, poor wound healing, and other manifestations. It may present in conjunction with autonomic, neurologic, and immune abnormalities. Hypermobility spectrum disorder is similarly characterized by joint hypermobility but holds less extensive diagnostic criteria. When in the hospital setting, systemic differences resulting from hypermobility syndromes must be recognized to avoid harm. Here, we present the first case, to our knowledge, of a full hospital course with hypermobility syndrome–comorbidity-related complications described.
Renal Sarcoidosis Presenting as Fanconi Syndrome | Annals of Internal Medicine: Clinical Cases
Fanconi syndrome is an extremely rare complication of renal sarcoidosis. We describe a case of biopsy-proven granulomatous interstitial nephritis secondary to sarcoidosis with the rare presenting feature of Fanconi syndrome. Our patient successfully received steroids initially, followed by mycophenolate and infliximab. These findings provide clinicians an important insight in recognizing this rare complication of sarcoidosis and opportunity to consider alternative regimens that can avoid or reduce side effects of first-line steroid therapy.
Concurrent Infective Endocarditis and Empyema From Salmonella arizonae | Annals of Internal Medicine: Clinical Cases
Although often associated with gastroenteritis, up to 30% of Salmonella infections are extraintestinal. Fewer than 50 cases of Salmonella empyema have been reported in the past century, and less than 2.9% of bacterial endocarditis cases are attributed to Salmonella species. Salmonella enterica subspecies arizonae generally causes mild disease and has been associated with reptiles or products containing rattlesnakes. We report the patient case of a 38-year-old man who presented to the hospital in septic shock and was found to have concurrent Salmonella bacteremia, endocarditis, and empyema with subspecies arizonae.
Pulmonary Mucormycosis With Dissemination: A Case of Unrelenting Fever and Chest Pain | Annals of Internal Medicine: Clinical Cases
Pulmonary mucormycosis is a rare entity that requires a high index of clinical suspicion for diagnosis. Untreated mucormycosis results in dissemination with exceedingly high mortality rates. Here, we present the patient case of a previously healthy 21-year-old man who presented with fever, dyspnea, chest pain, and progressive pulmonary consolidation. This patient case highlights the expanded differential diagnosis of presumed bacterial pneumonia that fails to respond to initial management and details the clinical, radiographic, and pathologic findings consistent with diagnosing pulmonary mucormycosis.