Two-dose recombinant shingles vaccine is effective even accounting for prior receipt of live shingles vaccine

Submitted by on Wed, 10/15/2025 - 3:28 PM EDT

External URL

https://www.acpjournals.org/doi/10.7326/ANNALS-24-02409

ACP Lastest Link Type

Annals of Internal Medicine

Summary

Recombinant zoster vaccine is effective in older adults, including immunocompromised adults, and 2 doses were more effective than 1. Prior ZVL recipients should be revaccinated with RZV.