MKSAP 19 "Quiz Me!" Question

Test your medical knowledge each month with questions from The Medical Knowledge Self-Assessment Program® (MKSAP).


For over 50 years, the Medical Knowledge Self-Assessment Program (MKSAP) has been the most trusted resource in continuous learning for internal medicine physicians and residents. The tradition continues with MKSAP 19.

MKSAP 19, to be released in early 2022, is available in several flexible formats, allowing you to choose the format that best fits your lifestyle. Each format includes 12 syllabus sections and 1,200 associated deep-learning self-assessment questions.

Learn about the new features in MKSAP 19, as well as pricing and release dates.


A 45-year-old woman is evaluated during a follow-up visit for newly diagnosed severe hypertension. She began low-dose hydrochlorothiazide and amlodipine therapy 1 month ago. There is no family history of hypertension. She has no other medical problems and takes no other medications.

On physical examination, blood pressure is 164/100 mm Hg in both arms, pulse rate is 76/min, and respiration rate is 18/min. BMI is 24. The remainder of the examination is normal.

Which of the following is the most appropriate diagnostic test to perform next?

A: Plasma aldosterone concentration/plasma renin activity ratio
B: Plasma fractionated metanephrines measurement
C: Renal artery CT angiography
D: 24-Hour urine free cortisol measurement

Answer and Critique

Back to the February 2022 issue of ACP IMpact