| 1927-32 | William H. Deaderick, Hot Springs |
| 1932-47 | Oliver Clarence Melson, Little Rock |
| 1947-56 | Arless A. Blair, Fort Smith |
| 1956-62 | John N. Compton, Little Rock |
| 1962-71 | Jerome S. Levy, Little Rock |
| 1971-75 | Robert S. Abernathy, Little Rock |
| 1975-79 | Joseph Henry Bates, Little Rock |
| 1979-83 | James E. Doherty III, Little Rock |
| 1983-87 | Joe B. Hall, Fayetteville |
| 1987-91 | George L. Ackerman, Little Rock |
| 1991-95 | James S. Adamson, Jr., Little Rock |
| 1995-99 | Taylor A. Prewitt, Fort Smith |
| 1998-2000 | William E. Golden, Little Rock (Transitional Governor) |
| 1999-2003 | Robert W. Bradsher, Jr., Little Rock |
| 2003-2007 | Ray Hall, Jr., Jonesboro |
| 2007-2011 | Robert Hopkins, Jr., Little Rock |
| 2011-2015 | Clark Fincher, MD, FACP, Little Rock |
| 2015-2019 | Omar Atiq, MD, FACP, Little Rock |
| 2019-2023 | Stacy C Zimmerman, MD, FACP, FAAP, Fayetteville |