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Clinical Guildelines

  1. Current Diagnosis of Venous Thromboembolism in Primary Care: A Clinical Practice Guideline from the American Academy of Family Physicians and the American College of Physicians
  2. Validated clinical prediction rules should be used to estimate pretest probability of venous thromboembolism (VTE), both deep venous thrombosis (DVT) and pulmonary embolism, and for the basis of interpretation of subsequent tests.
  3. In appropriately selected patients with low pretest probability of DVT or pulmonary emobolism, obtaining a high-sensitivity D-dimer is a reasonable option, and if negative indicates a low likelihood of VTE.
  4. Ultrasound is recommended for patients with intermediate to high pretest probability of DVT in the lower extremities.
  5. Patients with intermediate or high pretest probability of pulmonary emobolism require diagnostic imaging studies.

American College of Physicians