Hematology

Activated partial thromboplastin time — 25-35 s

Bleeding time — Less than 10 min

Coagulation factors, plasma

Factor I - 150-350 mg/dL (1.5-3.5 g/L)

Factor II - 60%-150% of normal

Factor V - 60%-150% of normal

Factor VII - 60%-150% of normal

Factor VIII - 60%-150% of normal

Factor IX - 60%-150% of normal

Factor X - 60%-150% of normal

Factor XI - 60%-150% of normal

Factor XII - 60%-150% of normal

D-dimer — less than 0.5 µg/mL (500 mg/L)

Erythrocyte count — 4.2-5.9 million cells/µL (4.2-5.9 x 10¹² cells/L)

Erythrocyte survival rate (⁵¹Cr) — T½ = 28 days

Erythropoietin — less than 30 mU/mL (30 U/L)

Ferritin — 15-200 ng/mL (15-200 mg/L)

Glucose-6-phosphate dehydrogenase, blood — 5-15 U/g Hgb (0.32-0.97 mU/mol Hgb)

Haptoglobin, serum — 50-150 mg/dL (500-1500 mg/L)

Hematocrit — Male: 41%-51%; female: 36%-47%

Hemoglobin, blood — Male: 14-17 g/dL (140-170 g/L); female: 12-16 g/dL (120-160 g/L)

Hemoglobin, plasma — 0.5-5 mg/dL (0.08-0.8 µmol/L)

Leukocyte alkaline phosphatase — 15-40 mg of phosphorus liberated/h per 10¹⁰ cells; score = 13-130/100 polymorphonuclear neutrophils and band forms

Leukocyte count — Nonblacks: 4000-10,000/µL (4.0-10 x 10⁹/L); Blacks: 3500-10,000/µL (3.5-10 x 10⁹/L)

Lymphocytes

CD4+ cell count — 640-1175/µL (0.64-1.18 × 10⁹/L)

CD8+ cell count — 335-875/µL (0.34-0.88 × 10⁹/L)

CD4: CD8 ratio — 1.0-4.0

Mean corpuscular hemoglobin (MCH) — 28-32 pg

Mean corpuscular hemoglobin concentration (MCHC) — 32-36 g/dL (320-360 g/L)

Mean corpuscular volume (MCV) — 80-100 fL

Osmotic fragility of erythrocytes — Increased if hemolysis occurs in over 0.5% NaCl, decreased if hemolysis is incomplete in 0.3% NaCl

Platelet count — 150,000-350,000/µL (150-350 × 10⁹/L)

Platelet life span (⁵¹Cr) — 8-12 days

Protein C activity, plasma — 67%-131%

Protein C resistance — 2.2-2.6

Protein S activity, plasma — 82%-144%

Prothrombin time — 11-13 s

Reticulocyte count — 0.5%-1.5% of erythrocytes; absolute: 23,000-90,000 cells/µL (23-90 × 10⁹/L)

Schilling test (oral administration of radioactive cobalamin labeled vitamin B₁₂) — 8.5%-28% excreted in urine per 24-48 h

Sedimentation rate, erythrocyte (Westergren) — Male: 0-15 mm/h; female: 0-20 mm/h

Volume, blood

Plasma - Male: 25-44 mL/kg (0.025-0.044 L/kg) body weight; female: 28-43 mL/kg (0.028-0.043 L/kg) body weight

Erythrocyte - Male: 25-35 mL/kg (0.025-0.044 L/kg) body weight; female: 20-30 mL/kg (0.020-0.030 L/kg) body weight