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MKSAP® 12 Update - Introduction
Acknowledgments
The American College of Physicians–American Society of Internal Medicine (ACP–ASIM) gratefully acknowledges the special contributions of Steven Spadt (Director, Electronic Product Development, ACP–ASIM Medical Knowledge and Education Division), Sean O'Donnell (Software Developer), John McKnight (Technical Production Analyst), Adam Schuman (Multimedia Specialist), Valerie Dangovetsky (Administrator), and Michael Ripca (Electronic Publishing Specialist), to the development of the Medical Knowledge Self-Assessment Program® (MKSAP®) 12 Update CD-ROM.
Special Thanks
Reviewers of MKSAP 12 Update Multiple-Choice Questions
The ACP–ASIM, the editors, and the authors thank the following individuals who have reviewed the multiple-choice questions for the MKSAP 12 Update.

Patrick C. Alguire, MD, FACP
Director, Education and Career Development Department
American College of Physicians–American Society of Internal Medicine

Virginia U. Collier, MD, FACP
Clinical Assistant Professor of Medicine
Jefferson Medical College
Vice Chair and Residency Program Director
Department of Medicine
Christiana Care Health System
Wilmington, Delaware

Jack Ende, MD, FACP
Chief of Medicine
Presbyterian Medical Center
University of Pennsylvania Health System
Philadelphia, Pennsylvania

Paul E. Epstein, MD, FACP
Clinical Professor of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania

D. Theresa Kanya, MBA
Vice President, The Medical Knowledge and Education Division
American College of Physicians–American Society of Internal Medicine

Bernard A. Mason, MD, FACP
Clinical Associate Professor of Medicine
University of Pennsylvania
Pennsylvania Hospital
Philadelphia, Pennsylvania

Vincenza Snow, MD
Senior Medical Associate, Scientific Policy
American College of Physicians–American Society of Internal Medicine

Herbert S. Waxman, MD, FACP
Senior Vice President, The Medical Knowledge and Education Division
American College of Physicians–American Society of Internal Medicine

Howard H. Weitz, MD, FACP
Director, Division of Cardiology
Jefferson Heart Institute
Philadelphia, Pennsylvania

Continuing Medical Education Information
MKSAP 12 Update Learning Objectives
  1. Update your knowledge in 13 key areas of internal medicine
  2. Apply new clinical problem-solving skills to improve the health of your patients
  3. Pursue further in-depth study using critically reviewed evidence-based references
  4. Assess the current state of your knowledge in clinical medicine
Audience
MKSAP 12 Update is designed for physicians who provide personal, nonsurgical care to adults, specifically general internists, subspecialists who need to remain up to date in internal medicine, residents preparing for the certifying examination in internal medicine, and physicians preparing for recertification.

Accreditation
The American College of Physicians–American Society of Internal Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American College of Physicians–American Society of Internal Medicine designates this educational activity for a maximum of 30 hours in category 1 credit toward the AMA Physician's Recognition Award. Each physician should claim only those hours of credit that he/she actually spent in the educational activity.

General
You will need approximately 30 hours to complete this program, which is delivered exclusively in a CD-ROM format. To participate, read the syllabus, complete the multiple-choice questions in the Self-Assessment area, and submit your answers, as instructed. The program release date is Oct. 18, 2002. CME credit hours are available until the termination date of Oct. 18, 2005.

Faculty
Please see the list of contributors and their credentials on the opening interface of the CD-ROM. Disclosures of significant relationships with relevant commercial companies and organizations are also listed in this area.

Note
In December 1999, the Institute of Medicine (IOM) issued a report challenging the medical profession to work together with hospitals, nurses, the federal government, and other health professions to improve patient safety and reduce avoidable medical errors that may lead to patient injury or death. The ACP–ASIM actively supports the goals of the IOM to improve the quality of patient care and to protect patient safety.

The editors and publisher of Medical Knowledge Self-Assessment Program 12 Update recognize that the development of new material offers many opportunities for error. Despite our best efforts, some errors may persist into print. Drug dosage schedules are, we believe, accurate and in accordance with current standards. Readers are advised, however, to ensure that the recommended dosages in MKSAP 12 Update concur with the information provided in the product information material. This is especially important in the case of new, infrequently used, or highly toxic drugs.

Publisher's Information
Copyright © 2002 American College of Physicians–American Society of Internal Medicine. All rights reserved.

Important copyright information from the ACP–ASIM:
Unauthorized reproduction of this publication is unlawful. The ACP–ASIM prohibits reproduction of this publication in its entirety in any form either for individual use or for distribution.

The ACP–ASIM will consider granting an individual permission to reproduce only limited portions of this publication for his or her own exclusive use. Send requests in writing to MKSAP®, American College of Physicians–American Society of Internal Medicine, 190 N. Independence Mall West, Philadelphia, PA 19106-1572.

ISBN: 1-930513-09-7
Library of Congress Catalog Number: 00-105021
Printed in the United States of America.