Annals of Internal Medicine is published by the American College of Physicians on the first and third Tuesday of every month. These highlights are not intended to substitute for articles as sources of information. For a copy of an article, call 1-800-523-1546, ext. 2656, or 215-351-2656, or visit www.annals.org. Past highlights are accessible as well.
(NOTE: This article is being released early online at www.annals.org. It will appear in the June 3, 2008, print edition of the journal.)
An evaluation of all randomized, controlled trials comparing sequential and standard triple therapies in patients with documented, previously untreated H. pylori infection found that sequential therapy appears superior to standard triple therapy for eradication of H. pylori infection. Authors say if further trials confirm these findings, 10-day sequential therapy could become a standard treatment for H. pylori infection in patients who have not received treatment.
(NOTE: This article and editorial is being released early online at www.annals.org. It will appear in the June 17, 2008, print edition of the journal.)
Editorial writers offer two paradigms for treatment. (Article, p. 717; Editorial, p. 783.)
A new study compared the incidence of different types of cancer among HIV-infected people with the incidence in the general population in the United States between 1992 and 2003 and found that certain cancers were more frequent among HIV-infected patients than among the general population (p. 728). Besides cancers that are common with AIDS, these included vaginal, liver, lung, mouth or throat, colon, and kidney cancer, leukemia, and melanoma. Authors say that patients with HIV infection and their doctors should be alert for signs of these types of cancer.