From "Can Evidence Change the Rate of Back Surgery?" Effective Clinical Practice, May/June 2001. 4:261-270.

Figure 3. Difference in low-back surgery (study minus control). A hinged, least-squares regression was fitted to this difference to test whether the rate of change in mean difference between the study and control communities (i.e., the slope of the difference regression) had significantly changed between baseline and intervention periods.
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