Internal Medicine Essentials for Clerkship Students

Hematology Section

Anemia (Chapter 38)

Iron Deficiency Anemia - View a peripheral blood smear showing hypochromic erythrocytes.

Microangiopathic Anemia - View a peripheral blood smear showing microangiopathic hemolytic anemia.

Spherocytosis - View a peripheral blood smear showing spherocytes.

Megaloblastic Anemia - View a peripheral blood smear showing megaloblastic anemia.

Target Cells - View a peripheral blood smear showing target cells.

Bite Cells - View a peripheral blood smear showing bite cells.

Acanthocytes - View a peripheral blood smear showing acanthocytes.

Sickle cells - View a peripheral blood smear showing sickle cells.

Drugs that Cause Macrocytosis - Review this table of drugs that commonly cause macrocytosis.

Macrocytic Anemia Algorithm - See an algorithm to assist you in the assessment of a macrocytic anemia.

Microcytic Anemia Algorithm - See an algorithm to assist you in the assessment of a microcytic anemia.

Bleeding Disorders (Chapter 39)

Hemophilia A and B Laboratory Evaluation - Use this table to guide the laboratory evaluation of hemophilia A and B.

Hereditary Hemorrhagic Telangiectasias - View telangiectasias associated with hereditary hemorrhagic telangiectasias (Osler-Weber-Rendu syndrome).

Laboratory Abnormalities in Hemophilia, vWD, and Platelet Function Defects - Use this table to distinguish between von Willebrand’s disease, hemophilia, and platelet function disorders.

Sickle Cell Anemia (Chapter 40)

Sickle Cells - View a peripheral blood smear showing sickle cells.

Dactylitis - View dactylitis involving the digits of the feet.

Hemoglobin Electrophoreses - Review this chart of hemoglobin electrophoresis patterns for various hemoglobinopathies.

Blood Transfusion - Review a list of indications for simple and exchange blood transfusions.

Laboratory Tests - Review this table of tests commonly used in the evaluation of sickle cell anemia.

Thrombocytopenia (Chapter 41)

Petechiae - View petechiae on the foot.

Pseudothrombocytopenia - View a peripheral blood smear showing platelet clumping characteristic of pseudothrombocytopenia.

Thrombotic thrombocytopenic purpura - View a peripheral blood smear showing schistocytes characteristic of thrombotic thrombocytopenic purpura.

Drug induced thrombocytopenia - See Annals of Internal Medicine for a systematic review of drugs causing thrombocytopenia.

Thrombophilia (Chapter 42)

Laboratory Evaluation - Use this table to review the common laboratory and other studies for the thrombophilias.

Anticoagulant Therapy - Review recommendations for the duration of anticoagulant therapy for patients with deep venous thrombosis.

Common Leukemias (Chapter 43)

Peripheral Blood Smear - Review these notes to help you differentiate the peripheral smear findings of the leukemias.

Chronic Myeloid Leukemia - View a peripheral blood smear characteristic of chronic myeloid leukemia.

Staging System for Chronic Myeloid Leukemia - Review the staging system for chronic myeloid leukemia.

Differential Diagnosis of Chronic Myeloid Leukemia - Review the differential diagnosis of chronic myeloid leukemia.

Auer Rod - View a peripheral blood smear showing an Auer rod.

Laboratory Studies for Acute Myeloid Leukemia - Review the laboratory studies to evaluate acute myeloid leukemia.

Differential Diagnosis of Acute Myeloid Leukemia - Review the differential diagnosis of acute myeloid leukemia.

Chronic Lymphocytic Leukemia - View a peripheral blood smear characteristic of chronic lymphotic leukemia.

Smudge Cell - View a smudge cell characteristic of chronic lymphocytic leukemia.

Staging System for Chronic Lymphocytic Leukemia - Review the Rai and Binet staging systems for chronic lymphocytic leukemia.

Differential Diagnosis for Chronic Lymphocytic Leukemia - Review the differential diagnosis for chronic lymphocytic leukemia.

Laboratory Studies for Chronic Lymphocytic Leukemia - Review the laboratory studies for chronic lymphocytic leukemia.

Multiple Myeloma (Chapter 44)

Multiple Myeloma - View a bone marrow aspiration from a patient with multiple myeloma.

Serum Protein Electrophoresis - View a serum protein electrophoresis from a patient with multiple myeloma.

Rouleaux - View a peripheral blood smear showing rouleaux formation associated with multiple myeloma.

Lytic Bone Lesions - View multiple lytic bone lesions and pathological fracture of the humerus.