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ACP Clinical Guidelines

ACP Clinical Guidelines

ACP Clinical Practice Guidelines cover many areas of internal medicine, including screening for cancer or other major diseases, diagnosis, treatment and medical technology. Click here for more



Screening for HIV in Health Care Settings: A Guidance Statement from the American College of Physicians and HIV Medicine Association

20 January 2009 | Volume 150 Issue 2

Guidance Statement 1: ACP recommends that clinicians adopt routine screening for HIV to encourage patients to be tested.

Guidance Statement 2: ACP recommends that clinicians determine the need for repeat screening on an individual basis.



Using Second-Generation Antidepressants to Treat Depressive Disorders: A Clinical Practice Guideline from the American College of Physicians

18 November 2008 | Volume 149 Issue 10 | Pages 725-733

Recommendation 1: The American College of Physicians recommends that when clinicians choose pharmacologic therapy to treat patients with acute major depression, they select second-generation antidepressants on the basis of adverse effect profiles, cost, and patient preferences (Grade: strong recommendation; moderate-quality evidence).

Recommendation 2: The American College of Physicians recommends that clinicians assess patient status, therapeutic response, and adverse effects of antidepressant therapy on a regular basis beginning within 1 to 2 weeks of initiation of therapy (Grade: strong recommendation; moderate-quality evidence).

Recommendation 3: The American College of Physicians recommends that clinicians modify treatment if the patient does not have an adequate response to pharmacotherapy within 6 to 8 weeks of the initiation of therapy for major depressive disorder (Grade: strong recommendation; moderate-quality evidence).

Recommendation 4:The American College of Physicians recommends that clinicians continue treatment for 4 to 9 months after a satisfactory response in patients with a first episode of major depressive disorder. For patients who have had 2 or more episodes of depression, an even longer duration of therapy may be beneficial (Grade: strong recommendation; moderate-quality evidence).



Pharmacologic Treatment of Low Bone Density or Osteoporosis to Prevent Fractures: A Clinical Practice Guideline from the American College of Physicians

16 September 2008 | Volume 149 Issue 6 | Pages 404-415

Recommendation 1: ACP recommends that clinicians offer pharmacologic treatment to men and women who have known osteoporosis and to those who have experienced fragility fractures (Grade: strong recommendation; high-quality evidence).

Recommendation 2: ACP recommends that clinicians consider pharmacologic treatment for men and women who are at risk for developing osteoporosis (Grade: weak recommendation; moderate-quality evidence).

Recommendation 3: ACP recommends that clinicians choose among pharmacologic treatment options for osteoporosis in men and women on the basis of an assessment of risk and benefits in individual patients (Grade: strong recommendation; moderate-quality evidence).

Recommendation 4: ACP recommends further research to evaluate treatment of osteoporosis in men and women.


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