From The American College of Physicians: The First 75 Years. Annals of Internal Medicine, 1 June 1990. 112:872-878.

Figure 2. Top Left. The first Philadelphia
headquarters for the college were located in the Covington Hotel
(no longer standing), 37th Street above Chestnut Street.
Top Right. The second Philadelphia headquarters
were located in what was then known as the Integrity Trust
Building, the northeast corner of 36th and Walnut Streets, adjacent
to the campus of the University of Pennsylvania. Source: Morgan WG.
American College of Physicians: Its First Quarter Century.
Philadelphia: American College of Physicians; 1940. Bottom
Left. The first permanent College Headquarters, 4200 Pine
Street, Philadelphia, 1936-1989. At right is the historic Eisenlohr
Mansion (1905), purchased by the College in 1936; the center wing
was added in 1961; destroyed by fire and rebuilt in 1966; the last
wing (left) was added in 1971, on the site of a one-time
mid-19th century residence occupied by the Group Insurance
Administrators affiliated with the College. Source: Archives of the
American College of Physicians. Bottom Right. The
current headquarters, completed in 1989, on Independence Mall West,
Sixth Street at Race in Philadelphia. Source: Department of News
and Information, American College of Physicians.