Associates' Presentations
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Case report of a dairy farmer with overdose of the veterinary tranquilizer, Zylazine.
Michelle Bensen, M.D., (Associate), Marshfield Clinic/St. Joseph's Hospital, Marshfield, WI.
Xylazine is a veterinary immobilizing agent that has been identified as a drug of abuse and misuse in humans. Unfortunately, medical doctors have had little if any experience with this drug, as it has been tested in a limited fashion in humans. There have been eleven case reports of human use of this drug either with suicidal, accidental or abuse intent. Over a one year time, the authors have become aware of two additional cases which are reviewed in this article. This drug is controlled under schedule 1, part 1, of the Federal Food & Drug Act and as such may be used only on animals "under the direct supervision of a licensed veterinarian." This medicine is available in injectable form only but has been shown through several case reports to also be absorbed orally. Since xylazine is not used in human medicine the range of effects reported from bradycardia to apnea have been categorized in this review. Hopefully, this will be helpful for emergency situations when physicians encounter overdose patients with an unknown substance.
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