Associates' Presentations
| Intro | Prev | Next | Last |
Cerebral Venous Thrombosis In A Patient With Protein S Deficiency
Radhika Raj, M.D., James Sebastian, M.D., Medical College of Wisconsin, Milwaukee, WI
Case: 23 year old male presented with acute onset of left sided weakness, numbness, blurred vision and occipital headache following minor head trauma. His past history was significant for Protein S deficiency for which he was on warfarin. Physical examination revealed limited left lateral gaze, left facial weakness, tongue deviation to the right, decreased sensation, dense motor weakness and a Babinski on the left. Investigations were significant for INR of 2.36 and Factor V Leiden mutation. Magnetic Resonance Imaging of the brain showed decreased signal intensity in the right sigmoid and transverse sinus. The patient was treated with Heparin with dramatic improvement within hours and complete neurologic recovery in 72 hours.
Discussion: Cerebral venous thrombosis can be caused by a wide variety of intracranial and systemic causes, has an extremely wide spectrum of clinical presentation and unpredictable course, thus presenting a challenge for the clinician. Combination of MRI and MRA is the best noninvasive method for the diagnosis and follow up of cerebral venous thrombosis. CVT is far more common than was previously assumed. Treatment of CVT with Heparin is associated with good results and its benefit exceeds the risk of hemorrhage. The outcome is usually favorable. This clinical vignette emphasizes that CVT should be considered in the appropriate clinical setting.
| Intro | Prev | Next | Last |
What's New
Contact Information
Sharon Haase, MD, FACP
Chapter Governor
Kelly Lang
Chapter Support Staff
Ph: 414-755-6280
E-mail: lang@svinicki.com