2001 Associates' Presentations

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Left Eye Blindness in Multiple Myeloma

M. Azimi-Zavarei, M.D.
G. Shapiro, M.D.
University of Wisconsin, Sinai Samaritan Medical Center, Milwaukee, Wisconsin

Case: A 76-year-old female presented with right shoulder pain, ptosis and loss of vision in the left eye. Her past medical history was significant for hip fracture. The work up was positive for Multiple Myeloma, and a 4x4 cm brain mass was found in suprasphenoid region.

Biopsy of the brain mass confirmed plasmacytoma. Patient was started on decadron and radiation therapy with excellent response. During hospital course ptosis improved almost completely and pain was under reasonable control. She was transferred to nursing home.

Discussion: Multiple Myeloma could involve every organ in the body. Some of the organs are involved less commonly including CNS. Meningial involvement is more common but brain parenchymal involvement occurs less frequent.

The intracerebral plasmocytoma will present with mass effect. Because of the excellent response to radiation therapy, biopsy is required for definite diagnosis. If patient doesn't die of usual complications of the Myeloma the prognosis intracerebral lesion is promising.


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Sharon Haase, MD, FACP
Chapter Governor

Kelly Lang
Chapter Support Staff
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