1999 Resident Poster Competition
Ahmad Anjak, M.D.
St. Louis University
Diabetes Insipidus in a Patient With Coexisting Diagnosis of Sheehan's Syndrome and Mollaret's Syndrome
We present the first case report of evolvement of Diabetes Insipidus in a patient, 18 years after the established diagnosis of Sheehan's syndrome. Our patient also has documented occurrence of Mollaret's syndrome 12 years prior to the recent development of Diabetes Insipidus.
Diabetes Insipidus has been reported as a rare complication of Sheehan's syndrome. Our case report is unique, as the symptoms and the diagnosis of Diabetes Insipidus occurred about 18 years after the onset of Sheehan's Syndrome.
An important fact which ws observed in our patient was the corticosteroids aggravated the underlying Diabetes Insipidus. As the patient was non-compliant with the steroid replacement in the past and was more compliant now, might explain the delayed appearance of the symptoms of Diabetes Insipidus.
Interestingly, Herpes Simplex virus has been linked with Mollaret's syndrome as well as with development of Diabetes Insipidus. It is possible that Herpes Simplex virus was the etiologic agent of Mollaret's syndrome and Diabetes Insipidus in this patient.
Our case report emphasized that we should be aware of Diabetes Insipidus as a rare but established complication of Sheehans' syndrome and that corticosteroids can worsen an existing Diabetes Insipidus. Last but not the least, our case report speculates the possibility of an association between Mollaret's syndrome and Diabetes Insipidus.
Return to 1999 Table of Contents
What's New
Contact Information
Alan D Forker, MD MACP
Missouri Chapter Governor
Patrick Mills
Missouri Chapter Executive Director
